Line Bisgaard Jørgensen

MD, Department of Endocrinology , Ph.d-student

Volumetric Measurements for Monitoring Ulcer Healing of Diabetic Foot Ulcers and Venous Leg Ulcers

Diabetic foot ulcers constitute an increasing health problem in Denmark concurrent with an ageing population and an increase in diabetes prevalence. Diabetic foot ulcers belong to the most serious and costly complications. Several studies have found that the size and depth of the wound is one of the major etiologic factors for delayed healing. Measurement of wound size is important in the monitoring of the wound healing process, and to evaluate the effect of treatment. Three-dimensional methods for measuring wound size have made it possible to evaluate the process of wound healing in relation to all dimensions.

We have developed a 3D camera, which is able to measure wound size (2D area, 3D area, perimeter and volume) and to assess wound characteristics.

Study 1:

The aim of the first study is to evaluate the intra- and inter-rater variability of wound measurements using the 3D camera and to compare the measurements with standard measurement methods (2D image method and gel injection).

Forty-eight patients with wounds of various sizes are measured by four clinicians. Each wound is measured twice with the 3D camera, once by 2D image method and once by gel injection into wound cavity by two clinicians.

Study 2:

The aim of the second study is to evaluate whether wound measurements using the 3D camera can provide new aspects of wound healing.

The study is a prospective cohort study in which newly admitted patients with a diabetic foot ulcer are included at the first visit at the University Centre for Wound Healing, Odense University Hospital. The wounds are measured by the 3D camera with frequent intervals, and the patients are followed for one year or until complete ulcer healing, amputation or death. Patient anthropometrics and wound data are collected during the study and correlated to the wound healing. 


The project seeks to clarify whether 3D photos of ulcers will provide precise measures to illuminate the background for delayed ulcer healing, and thereby to create a platform for a more evidence based treatment algorithm. The future vision is that a handheld 3D camera can be used in telemedical care of ulcer patients in the primary care sector as well as the specialized units at centres for wound treatment.


Knud Yderstræde, associate professor, Department of Endocrinology, Odense University Hospital

Jens Ahm Sørensen, Professor, Department of Plastic Surgery, Odense University Hospital

Gregor Jemec, Professor, Department of Dermatology, Roskilde Hospital

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